Mark Bloodworth has been experimenting with WPF and IronPython:
Having scanned a few pages, I decided to create a very simple app that included databinding and an event handler. Armed with Notepad++, XamlPad and a command prompt I set out.WPF is also used by Silverlight - which was originally called WPF/E - and is one of the few Microsoft projects to go from a boring codename to an interesting final release name; WPF itself was originally codenamed Avalon. WPF has a new set of controls, although still nothing like as many as Windows Forms, and uses an XML dialect called XAML for describing user interfaces.
First step was a little C#. I created a class as detailed here that adds a little dynamic-ness to WPF.
WPF was new in .NET 3.0, which added several new libraries to .NET 2.0 and is the base version of .NET that comes with Vista. It isn't a new version of the CLR (Common Language Runtime), but instead extends .NET 2.0. Both .NET 3.5 and .NET 2.0 SP1 have been released since .NET 3.0. Although several of the 3.0 libraries are being brought into Mono (see the Olive project), the Mono team have said in the past that they have no interest in porting WPF to run on Mono.
As the Silverlight UI is based on WPF and Moonlight (the Mono Silverlight implementation) is well on the way (Moonlight 1 is released and Moonlight 2 is progressing well) perhaps this decision will be revisited.